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T28167 |
NGB 2904
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NGB2904 HCl,NGB-2904,NGB2904 |
Others
,
Dopamine Receptor
,
5-HT Receptor
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NGB 2904 is a potent and selective antagonist of dopamine D3 receptor (Ki values are 1.4, 217, 223, 642, > 5000, > 10000 and > 10000 nM for D3, D2, 5-HT2, α1, D4, D1 and D5 receptors respectively). NGB2904 potently antag... |
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T2574 |
Alizapride hydrochloride
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Alizapride HCl |
Dopamine Receptor
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Alizapride hydrochloride (Alizapride HCl) is a dopamine receptor antagonist used for the treatment of nausea and vomiting. |
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T6604 |
Nepicastat hydrochloride
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Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl |
Hydroxylase
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Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta... |
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T1069 |
Metoclopramide hydrochloride
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Maxolon,Metoclopramide HCl |
Dopamine Receptor
,
5-HT Receptor
,
AChR
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Metoclopramide hydrochloride (Metoclopramide HCl) is a selective dopamine D2 receptor antagonist, used as an antiemetic. |
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T6988 |
SKF 38393 hydrochloride
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(±)-SKF-38393 hydrochloride,SKF-38393A,SKF38393 HCl |
Dopamine Receptor
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SKF 38393 hydrochloride (SKF38393 HCl) is a selective dopamine D1/D5 receptor agonist. |
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T28368 |
PF-04859989 HCl
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PF 04859989,PF04859989,PF-04859989HCl,PF-04859989 |
Others
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PF-04859989 HCl is a brain-penetrable irreversible inhibitor of kynurenine amino transferase II (KAT II), the enzyme responsible for most of the brain synthesis of kynurenic acid. PF-04859989 HCl has been implicated in s... |
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T8382 |
Cariprazine hydrochloride
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Cariprazine HCl,RGH188 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
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Cariprazine hydrochloride (RGH188 hydrochloride) is an antipsychotic drug, is a D3 and D2 receptor partial agonist((Ki of 0.085 nM and 0.49 nM, respectively) |
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T1735 |
Lurasidone hydrochloride
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Lurasidone HCl,SM-13496 (Hydrochloride),SM-13496 |
Dopamine Receptor
,
5-HT Receptor
,
Norepinephrine
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Lurasidone hydrochloride (Lurasidone HCl) is a thiazole derivative and atypical antipsychotic agent that functions as a dopamine D2 receptor antagonist; serotonin 5-HT2 receptor antagonist, serotonin 5-HT7 receptor antag... |
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T2592 |
Ropinirole hydrochloride
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SKF 101468 hydrochloride,SKF-101468A,Ropinirole HCl |
Dopamine Receptor
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Ropinirole hydrochloride (SKF-101468A) is a selective dopamine D2 receptors agonist (Ki: 29 nM). Ropinirole hydrochloride (SKF-101468A) is the hydrochloride salt form of ropinirole, a non-ergot dopamine agonist with anti... |
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T24047 |
Etilevodopa hydrochloride
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Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester |
Others
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Dopamine Receptor
,
Drug Metabolite
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|
Etilevodopa hydrochloride (L-DOPA ethyl ester) is a prodrug of levodopa. It also has greater gastric solubility and significant brain penetration. |
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T8136 |
Perospirone hydrochloride
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Perospirone HCl,SM-9018 hydrochloride |
Dopamine Receptor
,
5-HT Receptor
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Perospirone hydrochloride (Perospirone HCl) is an atypical antipsychotic agent for the treatment of schizophrenia. It also displays affinity towards 5HT1A receptors as a partial agonist. |
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T8690 |
Brexpiprazole HCl
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OPC 34712 dihydrochloride |
Others
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Brexpiprazole HCl (OPC 34712 dihydrochloride) is a new antipsychotic drug. |
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T21446 |
Rotigotine Hydrochloride
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Rotigotine (Hydrochloride),N 0923,N-0924,Rotigotine HCl,N-0923 |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
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|
Rotigotine Hydrochloride (N-0924), a dopamine receptor agonist prefering for D3 receptors over D1 and D2, has effective activity of anti-Parkinsonian. Racemic rotigotine hydrochloride is about 50 times as potent as quinp... |
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T0031L |
Ziprasidone hydrochloride
|
CP-88059 hydrochloride,CP-88059,Ziprasidone HCl |
Dopamine Receptor
,
5-HT Receptor
,
Adrenergic Receptor
,
Norepinephrine
,
Histamine Receptor
|
|
Ziprasidone hydrochloride (CP-88059 hydrochloride) is a united 5-HT (serotonin) and dopamine receptor antagonist which shows potent effects of antipsychotic activity. |
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T24797 |
SK609 HCl
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SK-609 HCl,SK609 hydrochloride,SK 609 HCl,SK 609 hydrochloride,SK-609 hydrochloride |
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SK609 HCl is a selective dopamine D3 receptor agonist. It also has atypical signaling properties. |
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T6142 |
PD128907 HCl
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|
Dopamine Receptor
|
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PD128907 HCl is a potent and selective dopamine D3 receptor agonist, with EC50 of 0.64 nM, exhibits 53-fold selectivity over dopamine D2 receptor. |
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T33711L |
Nolomirole HCl
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CHF 1035 HCl,CHF 1035,CHF1035,CHF1035 HCl,CHF-1035 HCl,CHF-1035,Nolomirole Hydrochloride |
Dopamine Receptor
,
Norepinephrine
|
|
Nolomirole HCl (CHF 1035) is a novel selective dopamine agonist with oral activity and inhibitory effects on norepinephrine release, which can be used to study mild chronic heart failure. |
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T0948 |
Adrenalone hydrochloride
|
Adrenalone HCl |
Adrenergic Receptor
|
|
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc... |
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T24399 |
Lenperone HCl
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|
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Lenperone HCl is a dopamine antagonist and an antipsychotic agent. |
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T69973 |
PF-04363467 HCl
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|
|
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PF-04363467 HCl is a selective dopamine D3/D2 receptor antagonist. |
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T24645 |
Piroheptine HCl
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Piroheptine Hydrochloride,Trimol |
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Piroheptine HCl is an agent of anticholinergic that acts by inhibiting dopamine uptake and completely preventing loss of striatal dopamine in MPTP-treated mice. |
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T27036 |
CL-216303 HCl
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DOV-216303,DOV216303,CL 216303,CL-216303,DOV 216303,CL216303 |
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CL-216303 HCl, a dopamine transporter inhibitor and a 5-HT inhibitor, is used potentially for the treatment of depression. |
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T70262 |
Sonepiprazole hydrochloride
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|
|
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Sonepiprazole HCl is a a selective dopamine D4 antagonist. |
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T33864 |
PAL-545 HCl
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PAL-545 Hydrochloride,PAL545 Hydrochloride,PAL 545 Hydrochloride |
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PAL-545 HCl is a type of releaser of dual dopamine-serotonin (DA/5-HT) . |
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T28640 |
S(+)-MDO-NPA HCl
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|
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S(+)-MDO-NPA HCl is an inhibitor of dopamine with oral activity, selective for rat limbic system. |
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T68767 |
Mezilamine HCl
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|
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Mezilamine HCl is a dopamine antagonist, blocking presynaptic but stimulating postsynaptic alpha-adrenoceptors. |
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T29241 |
(-)-MDO-NPA HCl
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|
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(-) -Mdo-NPA HCl is an oral effective long-acting drug that is active against central dopamine receptors and the similar apophin. |
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T69549 |
Ethybenztropine HCl
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|
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Ethybenztropine HCl is an anticholinergic which is used as an antiparkinsonian agent. Ethybenztropine may also act as a dopamine reuptake inhibitor. |
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T6356 |
(R)-Nepicastat HCl
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RS-25560-198 HCl |
Hydroxylase
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|
(R)-Nepicastat HCl (RS-25560-198 HCl), the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for tw... |
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T1552L |
Itopride free base
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HSR803,HSR-803,Itopride hydrochloride,HSR 803 |
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Itopride HCl is an AChE inhibitor and dopamine D2 receptor antagonist. It inhibits lower esophageal sphincter relaxation. It also used to treat functional dyspepsia and gastroesophageal reflux disease |
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T70155 |
Fenoldopam hydrochloride
|
|
|
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Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist... |
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T69991 |
Difenamizole HCl
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|
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Difenamizole HCl is the salt form of Difenamizole, a non-steroidal anti-inflammatory drug (NSAID) and analgesic of the pyrazolone group related to metamizole. It has monoaminergic properties, including inhibition of mono... |
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T27689 |
JNJ-7925476 HCl
|
JNJ-7925476,JNJ7925476,JNJ 7925476 |
|
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JNJ-7925476 HCl is a triple monoamine uptake inhibitor. JNJ-7925476 Salt blocks the dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter (SERT) in the central nervous system. The ED(50) ... |
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T68706 |
Olanzapine HCl
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|
|
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Olanzapine HCl is an atypical antipsychotic. It is approved by the U.S. Food and Drug Administration (FDA) for the treatment of schizophrenia and bipolar disorder. Olanzapine is structurally similar to clozapine and quet... |
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T69129 |
Clozapine HCl
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|
|
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Clozapine HCl is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serot... |
